Organo-Metalloid Compounds
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- (1)
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- (1)
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Filtered Search Results
![Medchemexpress LLC Hydroxylamine, O-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethyl]- | 1306615-51-9 | MFCD28505530 | 95.0% | 234.25 g/mol | C8H18N4O4 | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000202088.png-250.jpg)
Medchemexpress LLC Hydroxylamine, O-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethyl]- | 1306615-51-9 | MFCD28505530 | 95.0% | 234.25 g/mol | C8H18N4O4 | 10 MG
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Aminooxy-PEG3-azide is a PEG-based bifunctional linker containing an aminooxy (oxyamine) group and an azide group. It is used as a non-cleavable three-unit PEG spacer for antibody-drug conjugate (ADC) and PROTAC synthesis, and as an azide reagent for click chemistry reactions such as CuAAC and SPAAC.
- Bifunctional aminooxy and azide groups for oxime ligation and click chemistry.
- Non-cleavable three-unit PEG spacer suitable for ADC and PROTAC linker installation.
- Purity 95.0% and molecular weight 234.25 g/mol.
- Appearance colorless to light yellow liquid for easy handling.
- Storage: pure form -20°C (stable 3 years); in solvent -80°C (6 months) or -20°C (1 month).
- Available in small pack sizes, including 10 mg for small-scale synthesis.
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Medchemexpress LLC 4,7,10-trioxa-3-siladodecan-12-ol, 2,2,3,3-tetramethyl- | 201037-95-8 | MFCD30471718 | ≥98.0% | 264.43 g/mol | C12H28O4Si | 250 MG
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TBDMS-PEG3-OH is a tert-butyldimethylsilyl (TBDMS)-protected PEG3 alcohol used as a linker or spacer in organic synthesis, PROTAC construction, and drug-delivery conjugation. It provides a protected terminal alcohol for selective deprotection and coupling reactions.
- Provides a TBDMS-protected terminal alcohol for selective deprotection and coupling.
- Suitable as a PEG3 linker or spacer in medicinal chemistry and PROTAC synthesis.
- High purity (≥98%) and molecular weight 264.43 g/mol.
- Liquid, colorless to light yellow, convenient for solution-phase reactions.
- Recommended storage: pure form -20°C (long term) or 4°C (short term); in solvent store at -80°C.
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Medchemexpress LLC NH-bis(PEG3-azide) | 1258939-39-7 | 98.0% | C16H33N7O6 | 250 MG
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NH-bis(PEG3-azide) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It is also a click chemistry reagent, containing an Azide group, and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups, and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- Peg-based protac linker
- Used in the synthesis of protacs
- Functions as a click chemistry reagent
- Contains an azide group
- Capable of copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with alkyne groups
- Capable of strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups
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Medchemexpress LLC Bromoacetamido-PEG3-NH-Boc | 1421933-39-2 | C15H29BrN2O6 | 5 G
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Bromoacetamido-PEG3-NH-Boc is a PEG-based PROTAC linker.
- Can be used in the synthesis of PROTACs.
- PROTACs contain two different ligands connected by a linker.
- One ligand is for an E3 ubiquitin ligase and the other is for the target protein.
- PROTACs exploit the intracellular ubiquitin-proteasome system.
- Selectively degrade target proteins.
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Medchemexpress LLC Azido-PEG5-triethoxysilane | 3025193-22-7 | MFCD31693730 | 95.0% | C22H46N4O9Si | 25 MG
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Azido-PEG5-triethoxysilane is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It functions as a click chemistry reagent due to its Azide group, which allows it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with molecules containing Alkyne groups. Additionally, it can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- Used in the synthesis of PROTACs.
- Functions as a click chemistry reagent.
- Contains an Azide group for copper-catalyzed azide-alkyne cycloaddition reactions.
- Can undergo strain-promoted alkyne-azide cycloaddition reactions.
- PROTACs enable selective degradation of target proteins via the intracellular ubiquitin-proteasome system.
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Medchemexpress LLC THP-PEG5-OH | 146395-14-4 | 25 MG
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THP-PEG5-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It is also described as a reference compound.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Reference compound
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Medchemexpress LLC NH2-PEG5-C6-Cl hydrochloride | 2241669-16-7 | 98.0% | 100 MG
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NH2-PEG5-C6-Cl hydrochloride is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- PROTACs contain two different ligands connected by a linker
- One ligand binds to an E3 ubiquitin ligase
- The other ligand targets a specific protein
- Leverages the intracellular ubiquitin-proteasome system
- For selective degradation of target proteins
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Medchemexpress LLC BnO-PEG5-OH | 57671-28-0 | 98.6% | 328.40 g/mol | C17H28O6 | 10 G
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BnO-PEG5-OH is a polyethylene glycol (PEG)-based PROTAC linker used to connect ligands in proteolysis targeting chimera (PROTAC) synthesis, providing spacer functionality and flexibility to aid target engagement and E3 ligase recruitment.
- Polyethylene glycol spacer with five ethylene glycol units.
- High purity suitable for research applications.
- Liquid, colorless to light yellow, density ≈ 1.10 g/cm3.
- Stable under recommended storage conditions for pure material and in solvent.
- Available in common laboratory pack sizes, including 10 g.
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Medchemexpress LLC Peg3-C4-Obn | 2381196-79-6 | 99.3% | 25 MG
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PEG3-C4-OBn is a polyethylene glycol (PEG)-based PROTAC linker. It is utilized in the synthesis of a potent SKG3 degrader based on PROTAC.
- Liquid appearance
- Colorless to light yellow
- Purity of 99.3%
- Molecular weight of 296.40
- Molecular formula C17H28O4
- Used as a PROTAC linker
- Soluble in DMSO: ≥ 100 mg/mL
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Medchemexpress LLC THP-PEG5-OH | 50MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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THP-PEG5-OH | 50MG
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC I-PEG5-OH 250mg
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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I-PEG5-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]
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Medchemexpress LLC 4,7,10-trioxa-3-siladodecan-12-ol, 2,2,3,3-tetramethyl- | 201037-95-8 | ≥98.0% | 264.43 g·mol-1 | C12H28O4Si | 500 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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TBDMS-PEG3-OH is a tert-butyldimethylsilyl (TBDMS)-protected PEG3 hydroxy derivative used as a linker or spacer in drug delivery and conjugation chemistry. It has formula C12H28O4Si, a molecular weight of 264.43 g·mol-1, and is provided at high purity for research use.
- used as a PEG linker for conjugation and spacer chemistry.
- TBDMS protection enables selective silyl-deprotection strategies.
- high purity (≥98.0%) suitable for research applications.
- available in multiple pack sizes for small- to medium-scale synthesis.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC 1,11-bis-maleimidotetraethyleneglycol | 86099-06-1 | 98.0% | 25 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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BM-PEG3 is a PEG-based PROTAC linker designed for the synthesis of PROTACs. PROTACs (Proteolysis Targeting Chimeras) comprise two distinct ligands joined by a linker: one ligand targets an E3 ubiquitin ligase, and the other targets a specific protein. These chimeras leverage the intracellular ubiquitin-proteasome system for the selective degradation of target proteins. This product is intended for research use only.
- Functions as a PEG-based PROTAC linker
- Utilized in the synthesis of PROTACs
- Features two distinct ligands connected by a linker
- Ligands target an E3 ubiquitin ligase and a target protein
- Employs the intracellular ubiquitin-proteasome system
- Designed for selective degradation of target proteins
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Ethanol, 2-[2-[2-[(tetrahydro-2H-pyran-2-yl)oxy]ethoxy]ethoxy]- | 60221-37-6 | 98.7% | 25 G
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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THP-PEG3-OH is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs feature two ligands connected by a linker, one for an E3 ubiquitin ligase and another for a target protein. This mechanism exploits the intracellular ubiquitin-proteasome system to selectively degrade specific target proteins.
- High purity of 98.7%
- Molecular weight of 234.29
- Chemical formula is C11H22O5
- Appears as a liquid
- Colorless to light yellow
- Utilizes the ubiquitin-proteasome system
- Selectively degrades target proteins
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Tos-PEG3 | 77544-68-4 | 97.0% | 304.36 | 100 G
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Tos-PEG3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Tos-PEG3 (structure 1) can also be used for the synthesis of 3'-aminooxy oligonucleotides solid supports.
- Peg-based protac linker
- Used in the synthesis of protacs
- Can be used for the synthesis of 3'-aminooxy oligonucleotides solid supports
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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